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KMID : 1007320170230030160
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Journal of the Korean Society of Menopause
2017 Volume.23 No. 3 p.160 ~ p.165
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Effect of Phytoestrogen on Depression and Anxiety in Menopausal Women: A Systematic Review
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Fattah Abolfazl
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Abstract
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Objectives: In this systematic review, the effectiveness of herbal medicines in improving depression and anxiety in menopausalwomen was assessed.
Methods: Three following databases were individually searched: MEDLINE (1966-March 2017), SCOPUS (1990-March 2017), andthe Cochrane Library (Cochrane Central Register of Controlled Trials; 2017).
Results: A total of 9 trials were included in this systematic review. Overall, soy was found to have a beneficial effect. Also, fennelhad a significant positive effect on menopausal women with depression and anxiety disorder, but not on healthy women. Redclover showed varying effects ranging from significant to non-significant on depression and anxiety. Moreover, kava was found tohave a significant beneficial effect on depression and anxiety at dose of 200 mg/days.
Conclusions: Our study demonstrated that herbal medicines could improve anxiety and depression in among menopausalwomen. However, the beneficial effect still remains indefinite due to the poor methodology. (J Menopausal Med 2017;23:160-165)
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KEYWORD
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Anxiety , Depression , Menopause , Phytoestrogens
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